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Managing Pain Associated with Peripheral Neuropathy

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Unlocking Relief: Understanding and Managing Neuropathy Pain

August 13, 202312 min read

Unlocking Relief: Understanding and Managing Neuropathy Pain

Are you tired of living with constant pain and discomfort caused by neuropathy? Look no further - we're here to help you unlock the relief you've been searching for. Neuropathy pain can be incredibly debilitating, affecting your quality of life and making even the simplest tasks a challenge. But fear not, because understanding and managing neuropathy pain is within your grasp. In this comprehensive guide, we will delve into the intricacies of neuropathy, exploring its causes, symptoms, and available treatment options. Whether you have been recently diagnosed or have been battling neuropathy for years, this guide will provide you with the knowledge and tools you need to take control of your pain and regain your independence. Say goodbye to sleepless nights and limited mobility - it's time to unlock the relief you deserve. Let's embark on this journey together and discover a life free from neuropathy pain.

What is neuropathy pain?

Neuropathy pain, also known as peripheral neuropathy, is a condition that affects the nerves outside of the brain and spinal cord. It occurs when these nerves become damaged or dysfunctional, leading to a wide range of symptoms such as pain, tingling, numbness, and weakness. The pain can be localized to a specific area or can be widespread, affecting multiple parts of the body. Most commonly, it is felt in the feet first. The first symptoms are usually at night and milder in nature, and at this level, it can be ignored or managed by simple methods such as a warm bath or over-the-counter creams. Doctors at this time tend to have a watch-and-see approach.

Neuropathy pain can have a significant impact on your daily life, making it difficult to perform simple tasks and affecting your overall well-being. The pain can range from mild to severe, and it may be constant or come and go in episodes. It can affect your ability to walk, sleep, and engage in activities you once enjoyed. However, with proper management and treatment, it is possible to alleviate neuropathy pain and improve your quality of life.

Causes of neuropathy pain

Neuropathy pain can have various causes, and identifying the underlying cause is essential in developing an effective treatment plan. One of the most common causes of neuropathy pain is diabetes. High blood sugar levels can damage the nerves over time, leading to neuropathy. Other medical conditions, such as kidney disease, liver disease, and autoimmune disorders, can also cause neuropathy pain. Infections, such as Lyme disease, shingles, and HIV, can damage the nerves and result in neuropathy. Additionally, certain medications, such as chemotherapy drugs, statins, and some antibiotics, can cause nerve damage and lead to neuropathy pain.

Neuropathy Pain

Neuropathy pain can be classified into 3 main groups of causes, including diabetes, chemotherapy, and the category of idiopathic. Idiopathic is merely the grouping we give to the causes that are unknown. Most sites will state that understanding the underlying cause of your neuropathy pain is crucial in determining the most effective treatment approach; however, I have found that this is somewhat overrated. Here is why: In some specific and rarer cases, the cause will determine the treatment approach. These are usually managed by your MD or perhaps a specialist in neurology or rheumatology is on the case. That said, the majority by far will fit into the 3 categories noted above. If it is Diabetic Peripheral Neuropathy, then of course, the management of the Diabetes is important. If it is Chemotherapy-Induced Peripheral Neuropathy, then beyond managing the pain in the usual ways, no different program is used. Lastly, if it is Idiopathic Peripheral Neuropathy, we do not know the cause, so what could we do besides the usual and customary treatments.

In some cases, neuropathy pain may be caused by trauma or injury to the nerves. Car accidents, falls, and sports injuries can all result in nerve damage and subsequent neuropathy pain. Additionally, repetitive motion or pressure on certain nerves, such as those in the wrist (carpal tunnel syndrome), can cause neuropathy. Genetic factors can also play a role in some forms of neuropathy pain. These categories are relatively easy to determine the cause as the history is known.

Proximal neuropathy is a phrase less commonly used but is very common. Here the nerve is damaged or irritated closer to the source of where it leaves the spine. Common causes here are disc bulge, spinal stenosis, neurogenic claudication, and piriformis syndrome. Each of these could be an article unto itself.

Symptoms of neuropathy pain

Neuropathy pain can manifest in a variety of ways, and the symptoms can vary depending on the underlying cause and the nerves affected. Common symptoms include:

1. Pain: The most common symptom of neuropathy is pain, which can range from a mild tingling or burning sensation to a severe, sharp pain. The pain may be constant or intermittent and can affect one or both sides of the body. It may worsen at night or after prolonged periods of sitting or standing. Generally, most diabetic peripheral neuropathy and neuropathies caused by chemotherapy involve both sides somewhat equally.

2. Numbness and tingling: Many people with neuropathy experience numbness and tingling in the affected areas. This can make it difficult to feel sensations such as temperature or touch. Often times the ground cannot be felt as one walks resulting in poor balance and thus falls.

3. Muscle weakness: Neuropathy can cause muscle weakness, making it challenging to perform tasks that require strength, such as lifting objects or climbing stairs.

4. Loss of coordination: Some individuals with neuropathy may experience a loss of coordination, making it difficult to walk or perform fine motor tasks. This happens because the brain cannot sense what the feet or other areas are doing. When this happens the walking style changes, and activities are decreased due to fear of falling.

5. Sensitivity to touch: In some cases, neuropathy can cause hypersensitivity to touch, resulting in pain or discomfort with even light pressure. This is classically felt at night when the bed sheets cause extreme pain with the lightest pressure.

It's important to note that not everyone with neuropathy will experience all of these symptoms, and the severity of symptoms can vary. If you are experiencing any of these symptoms, it is essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

Diagnosing neuropathy pain

Diagnosing neuropathy pain typically involves a thorough medical history review, physical examination, and various tests. Your healthcare provider will ask about your symptoms, medical history, and any underlying medical conditions that may be contributing to your neuropathy pain. During the physical examination, they may assess your reflexes, muscle strength, and coordination. They may also perform tests to evaluate your sensation, such as touching your skin with a soft brush or pricking it with a pin.

In addition to the physical examination, your healthcare provider may order various tests to help diagnose neuropathy pain. These tests may include:

Neuropathy Diagnosis

1. Nerve conduction studies: This test measures the speed and strength of electrical signals traveling through your nerves. It can help determine if your nerves are functioning properly.

2. Electromyography (EMG): EMG measures the electrical activity in your muscles and can help identify muscle weakness or muscle damage.

3. Blood tests: Blood tests can help identify underlying medical conditions that may be causing your neuropathy pain, such as diabetes, vitamin deficiencies, or autoimmune disorders.

4. Imaging tests: In some cases, imaging tests such as X-rays, CT scans, or MRI scans may be ordered to evaluate the nerves and surrounding structures.

Treatment options for neuropathy pain

The treatment of neuropathy pain aims to alleviate symptoms, slow down the progression of nerve damage, and address the underlying cause if possible. The treatment approach may vary depending on the severity of your symptoms, the underlying cause, and your overall health. It often involves a combination of medications, natural remedies, lifestyle changes, and self-care strategies. Let's explore some of the common treatment options for neuropathy pain.

Medications for managing neuropathy pain

Several medications may be prescribed to manage neuropathy pain, depending on the type and severity of your symptoms. These medications can help alleviate pain, reduce inflammation, and improve nerve function. Common medications used for neuropathy pain include:

1. Over-the-counter pain relievers: Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, can help reduce mild to moderate neuropathy pain.

2. Topical medications: Creams or patches containing lidocaine or capsaicin can provide temporary relief by numbing the affected area or reducing pain signals.

3. Antidepressants: Certain antidepressant medications, such as amitriptyline or duloxetine, can help relieve neuropathy pain by altering the brain's perception of pain.

Neighborhood Neuropathy Midwest

4. Anticonvulsants: Medications commonly used to treat seizures, such as gabapentin or pregabalin, can also be effective in reducing neuropathy pain by stabilizing nerve activity.

5. Opioids: In severe cases where other treatments have been ineffective, opioids may be prescribed for short-term pain relief. However, due to their potential for dependence and side effects, they are typically used as a last resort.

It's important to work closely with your healthcare provider when taking any medications for neuropathy pain to ensure proper dosage and monitoring of side effects. Medications alone may not provide complete relief, so it's essential to explore other treatment options as well.

Natural remedies for relieving neuropathy pain

In addition to medications, several natural remedies may help alleviate neuropathy pain and improve nerve function. These remedies can be used alongside conventional treatments to enhance the overall management of neuropathy pain. Here are some natural remedies to consider:

1. Acupuncture: Acupuncture involves the insertion of thin needles into specific points on the body to stimulate nerve function and alleviate pain. It has been found to be effective in reducing neuropathy pain in some individuals. There are several different approaches the practitioner may employ. This will be determined by the training and practice style. Needles may be inserted locally into the painful region, or a more traditional whole-body approach may be used. Both have been researched and are effective in some cases.

2. Supplements: Certain supplements, such as alpha-lipoic acid, vitamin B12, and acetyl-L-carnitine, have shown promise in reducing neuropathy pain and improving nerve health. Alpha-lipoic acid has its best effectiveness in those under 40. It works in the process to develop nitric oxide (NO). NO is a powerful vasodilator, meaning it will increase circulation where it is. After age 40, we need to look at increasing NO through another path, namely the Nitrate path. That will be a subject for another article.

3. Physical therapy: I have another article on this subject.

4. Transcutaneous electrical nerve stimulation (TENS): TENS involves the use of low-voltage electrical currents applied to the skin to reduce pain and improve nerve function. It can be an effective non-invasive option for managing neuropathy pain. This is an underused and less expensive option that one can use at home.

Lifestyle changes for managing neuropathy pain

Making certain lifestyle changes can also play a significant role in managing neuropathy pain and improving your overall well-being. Here are some lifestyle changes to consider:

1. Maintain a healthy diet: A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can help support nerve health and overall well-being. Avoiding excessive sugar and processed foods is especially important for individuals with diabetes-related neuropathy.

2. Exercise regularly: Regular physical activity, such as walking, swimming, or cycling, can help improve circulation, reduce pain, and improve overall nerve function. While this is good advice and is supported by research, I have found that many neuropathy sufferers are unable to do much exercise, either due to the limitations of the neuropathy itself or from other health issues. I will explore this more thoroughly in another article.

3. Manage stress: Chronic stress can exacerbate neuropathy pain. Engaging in stress-reducing activities such as meditation, deep breathing exercises, or yoga can help alleviate pain and improve overall well-being.

4. Practice good foot care: If you have neuropathy pain in your feet, it's crucial to take extra care of your feet to prevent complications such as infections or ulcers. Regularly inspect your feet for any signs of injury or infection, keep them clean and dry, and wear appropriate footwear.

Coping with neuropathy pain emotionally

Living with neuropathy pain can take a toll on your emotional well-being. It's important to address the emotional impact of neuropathy pain and develop coping strategies to maintain a positive mindset. Here are some tips for coping with neuropathy pain emotionally:

1. Seek support: Reach out to friends, family, or support groups who can understand and empathize with your experience. Sharing your feelings and concerns can provide emotional support and help you feel less alone.

2. Practice relaxation techniques: Engage in activities that help you relax and unwind, such as deep breathing exercises, meditation, or listening to calming music. These techniques can help reduce stress and promote a sense of calm.

3. Focus on what you can control: While you may not be able to control your neuropathy pain, you can control how you respond to it. Focus on the things you can do to manage your symptoms and improve your overall well-being.

4. Engage in enjoyable activities: Find activities that bring you joy and engage your mind and body. Whether it's reading, painting, gardening, or listening to music, engaging in activities you enjoy can help distract from the pain and improve your mood.

When to seek professional help for neuropathy pain

While there are various self-care strategies and treatment options available for managing neuropathy pain, it's essential to know when to seek professional help. Consult with a healthcare professional if:


1. Your neuropathy pain is severe or worsening.

2. You experience new or worsening symptoms.

3. Your pain is interfering with your daily activities and quality of life.

4. You are experiencing side effects from your medications.

5. Your neuropathy pain is accompanied by other concerning symptoms, such as weakness or loss of bladder control.

A healthcare professional can evaluate your symptoms, adjust your treatment plan if necessary, and refer you to a specialist if needed.


Living with neuropathy pain can be challenging, but with the right knowledge and tools, it is possible to manage your symptoms effectively and regain control of your life. By understanding the causes, symptoms, and available treatment options for neuropathy pain, you can take proactive steps to alleviate your pain and improve your overall well-being. Remember to consult with a healthcare professional for an accurate diagnosis and personalized treatment plan. With determination and the right support, you can unlock the relief you deserve and embark

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